Post-operative analgesia.

Novel concepts of analgesia for post operative pain: Multimodal analgesia

Post-operative analgesia after remifentanil-based anaesthesia

Remifentanil is a very potent ultrashort acting opioid, that is mainly used as a part of balanced anaesthesia regimens for management of intraoperative pain. Effective plasma levels of this drug can only be maintained using continuous infusions, as tissue esterases inactivate remifentanil within minutes following its application. The advantages of this specific pharmacokinetic behaviour are tha...

Post-operative Analgesia in Opioid Dependent Patients: Comparison of ‎Intravenous Morphine and Sublingual Buprenorphine

Background: Acute and chronic pain is prevalent in patients with opioid dependence. Lack of knowledge concerning the complex relationship between pain, opioid use, and withdrawal syndrome can account for the barriers encountered for pain management. This study was designed to evaluate the efficacy of sublingual (SL) buprenorphine for post-operative analgesia, compared with intravenous (IV) morp...

Compartment syndrome obscured by post-operative epidural analgesia

Compartment syndrome is an orthopedic emergency that require early recognition and urgent intervention to avoid catastrophic complications. High index of suspicion is required for early diagnosis based on a constellation of signs and symptoms that include pain out of proportion and worsened by passive stretching, altered sensorium and palpable tenseness. Any event thus, that masks pain, may lea...

addition of clonidine in caudal anesthesia in children increases duration of post-operative analgesia

background: pain in infancy is a developmental process. due to the underdeveloped pain pathways in the spinal cord, the threshold of stimulation and sensation of pain is low at birth and has potential impacts on increasing the central effects of pain. primary trauma during infancy can cause long term changes in structure and function of pain pathways that continue until adulthood. lack of pain ...